Search results for " modèle"

showing 10 items of 22 documents

7-ketocholesterol and 7β-hydroxycholesterol: in vitro and animal models used to characterize their activities and to identify molecules preventing th…

2020

International audience; Oxysterols are molecules derived by the oxidation of cholesterol and can be formed either by auto-oxidation, enzymatically or by both processes. Among the oxysterols formed by auto-oxidation, 7-ketocholesterol and 7beta-hydroxycholesterol are the main forms generated. These oxysterols, formed endogenously and brought in large quantities by certain foods, have major cytotoxic properties. They are powerful inducers of oxidative stress, inducing dysfunction of organelles (mitochondria, lysosomes and peroxisomes) that can cause cell death. These molecules are often identified in increased amounts in common pathological states such as cardiovascular diseases, certain eye …

0301 basic medicine[SDV]Life Sciences [q-bio]CellmicrofluidicMitochondrionPharmacologiemedicine.disease_causeBiochemistry0302 clinical medicineanimal modèleKetocholesterolsComputingMilieux_MISCELLANEOUSCells CulturedsignalingpathwaysCell DeathChemistry7β-hydroxycholesterolNeurodegenerative DiseasesPeroxisomeanimal models3. Good healthmedicine.anatomical_structureBiochemistryCardiovascular Diseases030220 oncology & carcinogenesisToxicity[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]modèle cellulaireSignal transductionProgrammed cell deathCataractCell Line03 medical and health sciencesPharmaceutical sciencesCell Line TumormedicineAnimalsHumans[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologyhydroxycholestérol7-ketocholesterolPharmacologyOrganelles7-ketocholesterol;7β-hydroxycholesterol;cell models;animal models;microfluidic;signalingpathwaysInflammatory Bowel DiseasesIn vitroHydroxycholesterolscell modelsDisease Models Animal030104 developmental biologyvoie de signalisationSciences pharmaceutiques[SDV.AEN]Life Sciences [q-bio]/Food and NutritionOxidative stress
researchProduct

Le prix des paysages périurbains

2007

L'évaluation économique du prix des paysages périurbains utilise des analyses géographiques (occupation des sols, composition paysagère, distance à des biens paysagers, paysages vus : champ de vision, objets, formes). L'article fait le point sur la littérature en matière de méthode et de résultats et présente l'estimation du prix d'attributs paysagers dans la ceinture périurbaine de Dijon.

AMENITEamenityhedonic price[SHS.GEO] Humanities and Social Sciences/Geographymodèle[ SHS.GEO ] Humanities and Social Sciences/GeographypériurbainEconomies et financesaménité0502 economics and businesszone périurbainePRIX HEDONISTE050207 economicspaysageprix hédonisteliving environmentestimation05 social sciencesattribut paysagerperiurban[SHS.GEO]Humanities and Social Sciences/Geography15. Life on landPRIX HEDONISTE;CADRE DE VIE;AMENITE;LANDSCAPE;PERIURBAN;HEDONIC PRICE;LIVING ENVIRONMENT;AMENITYlandscape[SHS.ECO]Humanities and Social Sciences/Economics and FinanceEconomies and financesméthode050202 agricultural economics & policycadre de viePRIX HEDONISTE CADRE DE VIE AMENITE LANDSCAPE PERIURBAN HEDONIC PRICE LIVING ENVIRONMENT AMENITY paysage zone périurbaineattribut paysagerestimation modèleméthode
researchProduct

GEOV1: LAI, FAPAR essential climate variables and FCOVER global time series capitalizing over existing products. Part 2: Validation and intercomparis…

2013

International audience; This paper describes the scientific validation of the first version of global biophysical products (i.e., leaf area index, fraction of absorbed photosynthetically active radiation and fraction of vegetation cover), namely GEOV1, developed in the framework of the geoland-2/BioPar core mapping service at 1 km spatial resolution and 10-days temporal frequency. The strategy follows the recommendations of the CEOS/WGCV Land Product Validation for LAI global products validation. Several criteria of performance were evaluated, including continuity, spatial and temporal consistency, dynamic range of retrievals, statistical analysis per biome type, precision and accuracy. The…

Accuracy and precision010504 meteorology & atmospheric sciencescouvert végétalcomparaison de modèlesBiomecritère de performanceSoil ScienceMagnitude (mathematics)Context (language use)01 natural sciencesGEOV1;Vegetation variables;Validation;GMES;Land monitoring core servicevalidation scientifiquefraction of absorbed photosynthetically active radiation (fAPAR)GEOV1ValidationfcoverFraction (mathematics)Computers in Earth SciencesLeaf area indexvariable climatiqueMilieux et Changements globauxfraction de couvert0105 earth and related environmental sciencesRemote sensinggmescarte de référenceanalyse statistiquefaparLand monitoring core serviceGeology04 agricultural and veterinary sciencesresolution spatiale15. Life on landComputer scienceLAIindice de surface foliaireSeaWiFSbiome13. Climate actionPhotosynthetically active radiationInformatique (Sciences cognitives)surveillance de l'environnement[SDE]Environmental Sciences040103 agronomy & agriculture0401 agriculture forestry and fisheriesEnvironmental scienceVegetation variables
researchProduct

Comprehending city and its production in Africa through a systemic approach : example of the city of Diamniadio, Dakar

2022

For a long time, the analysis of the production of the city in Africa was based on an exogenous perception according to urban models theorized and experimented with in the Occidental countries, then diffused and applied through different mechanisms in the South, bearing witness to historical relations - through the making of the colonial city - and present relations - in the context of the making of new towns. After independence, researchers looked at the redefinition of the city in Africa with its complexity and plurality according to geographical and historical trajectories, proposing new urban theories that were more nuanced and linked to local and contextual realities. Therefore, follow…

Circulation of urban modelsFormelleUrban metabolism[SHS.GEO] Humanities and Social Sciences/GeographyComplex urban systemVille organiqueInformelleNew citiesOrganic cityCirculation de modèles urbainsMétabolisme urbainEffective cityInformal cityVilles nouvellesSystème urbain complexeLiving cityVille vivante
researchProduct

Penalization and data reduction of auxiliary variables in survey sampling

2012

Survey sampling techniques are quite useful in a way to estimate population parameterssuch as the population total when the large dimensional auxiliary data setis available. This thesis deals with the estimation of population total in presenceof ill-conditioned large data set.In the first chapter, we give some basic definitions that will be used in thelater chapters. The Horvitz-Thompson estimator is defined as an estimator whichdoes not use auxiliary variables. Along with, calibration technique is defined toincorporate the auxiliary variables for sake of improvement in the estimation ofpopulation totals for a fixed sample size.The second chapter is a part of a review article about ridge re…

Estimateur assisté par un modèleModel-assisted estimatorRégression ridge[ MATH.MATH-GM ] Mathematics [math]/General Mathematics [math.GM]Calage sur composantes principalesPenalized calibration[MATH.MATH-GM] Mathematics [math]/General Mathematics [math.GM]Estimateur basé sur un modèleSurvey sampling[MATH.MATH-GM]Mathematics [math]/General Mathematics [math.GM]Ridge regressionCalage pénaliséModel-based estimatorColinéaritéEstimateur de Horvitz-ThompsonHorvitz-Thompson estimatorSondageMulticollinearityPrincipal component calibration
researchProduct

A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)

2018

AbstractThe Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable climates during its global invasion, and, notably, to rapidly evolve insecticide resistance. To examine evidence of rapid evolutionary change, and to understand the genetic basis of herbivory and insecticide resistance, we tested for structural and functional genomic changes relative to other arthropod species using genome sequencing, transcriptomics, and community annotation. Two factors that might facilitate rapid evolutionary change include transposable elements, which comprise at least 17% of the gen…

Male0106 biological sciences0301 basic medicineGenome Insectlcsh:Medicine01 natural sciencesGenomeNucleotide diversityInsecticide Resistancepomme de terreTRIBOLIUM-CASTANEUMlcsh:ScienceLeptinotarsaCYSTEINE PROTEINASESPhylogeny2. Zero hungereducation.field_of_studyGenomeMultidisciplinarybiologyinsecte ravageurEcologyGenètica vegetalAgricultureleptinotarsa decemlineataGenomicsS-TRANSFERASE GENESlutte contre les ravageursColeopteraOther Physical Sciencesphénotypeespèce modèleMultigene FamilyInsect ProteinsRNA InterferenceFemaleBiotechnologyAutre (Sciences du Vivant)Genome evolutiondoryphorecoleopteraEvolutionPopulationPopulationRNA-INTERFERENCEGenomicsGEOGRAPHIC POPULATIONSArticleDNA sequencingHost-Parasite InteractionsEvolution Molecular03 medical and health sciences[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]GeneticsAnimalsanalyse génomiquePest Control BiologicaleducationQH426GeneSolanum tuberosumComparative genomicsbusiness.industrychrysomelidaelcsh:RHuman GenomefungiColorado potato beetlePest controlBiology and Life SciencesMolecularGenetic VariationMolecular Sequence AnnotationBiologicalbiology.organism_classification010602 entomologyGenòmicaGenetics Population030104 developmental biologyGene Expression RegulationDROSOPHILA-MELANOGASTERPROTEINASE-INHIBITORSEvolutionary biologyTRANSPOSABLE ELEMENTSDNA Transposable Elementslcsh:QPest ControlBiochemistry and Cell BiologyPEST analysisCAENORHABDITIS-ELEGANSbusinessInsectTranscription Factors
researchProduct

Metabolic syndrome triggered by high-fructose diet favors choroidal neovascularization and impairs retinal light sensitivity in the rat

2014

Diabetic retinopathy and age-related macular degeneration are the leading causes of blindness in Western populations. Although it is a matter of controversy, large-scale population-based studies have reported increased prevalence of age-related macular degeneration in patients with diabetes or diabetic retinopathy. We hypothesized that metabolic syndrome, one of the major risk factors for type 2 diabetes, would represent a favorable environment for the development of choroidal neovascularization, the main complication of age-related macular degeneration. The fructose-fed rat was used as a model for metabolic syndrome in which choroidal neovascularization was induced by laser photocoagulatio…

MaleOrganes des sensmedicine.medical_treatment[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionVisual Acuitylcsh:MedicineGene ExpressionType 2 diabetesinduced insulin-resistanceanimal-modelscholesterol homeostasis0302 clinical medicineRetinal Rod Photoreceptor CellsRats Inbred BNHyperinsulinemiaMedicine and Health Sciencesanimal modèleratlcsh:Science2. Zero hungerMetabolic Syndrome0303 health scienceseducation.field_of_studyMultidisciplinaryLaser Coagulationsyndrome métaboliqueReverse Transcriptase Polymerase Chain Reactionhepatic steatosisFatty AcidsAngiographyDiabetic retinopathyChoroidal neovascularizationAdipose Tissue[ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansAlimentation et NutritionRetinal Disordersmedicine.symptomLaser coagulationResearch Articlediabètemedicine.medical_specialtymacular degenerationPopulationSensory Organselectroretinographic oscillatory potentials;induced insulin-resistance;fatty-acid profile;macular degeneration;diabetic-retinopathy;animal-models;cholesterol homeostasis;hepatic steatosis;mouse;associationAntigens Differentiation MyelomonocyticMédecine humaine et pathologieFructoseBiologyRetina03 medical and health sciencesAntigens CDDiabetes mellitusInternal medicine[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologymedicineElectroretinographyelectroretinographic oscillatory potentialsAnimalsHumansFood and Nutrition[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrganseducationRetinopathymouse030304 developmental biologyNutritiondiabetic-retinopathylcsh:RassociationBiology and Life Sciencesdégénérescence maculaireMacular degenerationmedicine.diseaseChoroidal Neovascularizationeye diseasesDietFatty LiverOphthalmologyEndocrinologyMetabolic Disordersfatty-acid profile030221 ophthalmology & optometrylcsh:QInsulinomaHuman health and pathologysense organs[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
researchProduct

Automatic production of three-dimensionnel models by 3D digitization

2012

The manual 3D digitization process is expensive since it requires a highly trained technician who decides about the different views needed to acquire the object model. The quality of the final result strongly depends, in addition to the complexity of the object shape, on the selected viewpoints and thus on the human expertise. Nowadays, the most developed digitization strategies in industry are based on a teaching approach in which a human operator manually determines one set of poses for the ranging device. The main drawback of this methodology is the influence of the operator's expertise. Moreover, this technique does not fulfill the high level requirement of industrial applications which…

Méthodes non-basées sur un modèle[INFO.INFO-OH] Computer Science [cs]/Other [cs.OH]AutomationAutomatisation[INFO.INFO-OH]Computer Science [cs]/Other [cs.OH][ INFO.INFO-OH ] Computer Science [cs]/Other [cs.OH]View planningPlanification de vueNumérisation 3DNext Best View3D digitization
researchProduct

Le potentiel innovant des nouvelles pratiques de GRH en question

2022

Pratiques managérialesInnovation ManagementGRH – innovation – stratégie – modèles[SHS.GESTION] Humanities and Social Sciences/Business administration
researchProduct

3D digitization of transparent objects by polalization techniques in IR & by triangulation in UV

2011

Two non-conventional methods for the 3D digitization of transparent objects via non-contact measurement are reported in this thesis. 3D digitization is a well acknowledged technique for opaque objects and various commercial solutions based on different measurement approaches are available in the market offering different types of resolution at different prices. Since these techniques require a diffused or lambertian surface, their application to transparent surfaces fails. Indeed, rays reflected by the transparent surface are perturbed by diverse inter-reflections induced by the refractive properties of the object. Therefore, in industrial applications like quality control, the transparent …

Reconstruction par polarisation dans l'IRLow cost systemApproximation du modèle orthographique[INFO.INFO-OH]Computer Science [cs]/Other [cs.OH]Objets transparentscoût)3D digitizationMéthode de validation des paramètres de StokesExcellent accuracyFluorescence tracking and characterizationTransparent objectsValidation method for optimal configuration setupScanning par laser UVIndustrialisable (en terme de précisionIndustrial applicationsOrthographic approximation approachShape from polarization in IRStokes parameters validation method[INFO.INFO-OH] Computer Science [cs]/Other [cs.OH]Scanning from UV laserMéthode de validation pour une configuration optimale du système[ INFO.INFO-OH ] Computer Science [cs]/Other [cs.OH]Non telecentric lenseNumérisation 3DLentille non télécentrique"tracking" et caractérisation de la fluorescence
researchProduct